Buy CBD Oil: Effects, Strength, Types, and Uses – Complete Guide

CBD oil has grown into one of the most purchased and most discussed natural supplements of recent years. In the Netherlands, where the discussion surrounding cannabis has been more nuanced for decades than in many other countries, CBD has found a broad and diverse user community: from people seeking relaxation after a busy workday to athletes looking to support recovery and seniors seeking mild, daily support for body and mind.

At Dr Smart Shop , CBD oil is available as part of the CBDshop category , specifically via the CBD Oil collection . The full range consists of products from the brand Cannabas – a quality brand with a wide and well-documented range of CBD oils in six different strengths, supplemented with CBG, CBC, and CBN oils and two cosmetic products. This article provides a complete informative overview of everything you need to know about CBD oil, from effects to dosage and product selection. The information is purely educational and does not constitute medical advice.

What is CBD and how does it work?

CBD – short for cannabidiol – is one of the more than one hundred known cannabinoids that occur naturally in the hemp plant ( Cannabis sativa L. ). It is the most abundant non-psychoactive cannabinoid in the plant and is extracted from the flowers, leaves, and stems via CO2 extraction or ethanol extraction. CBD oil is a solution of CBD extract in a carrier oil – in the case of Cannabas, a high-quality vegetable oil that optimizes the absorption of CBD by the body.

Unlike THC – the well-known psychoactive cannabinoid that causes a "high" – CBD has no psychoactive effect . It does not affect cognition, consciousness, or perception in a way that is perceived as intoxicating. All CBD products in the Dr Smart Shop range contain less than 0,2% THC and are fully legal in the Netherlands and the entire European Union.

The action of CBD occurs primarily via the endocannabinoid system – an extensive signaling network in the human body that plays a central role in the regulation of numerous physiological processes, including pain, inflammation, mood, sleep, appetite, and the immune system.

The endocannabinoid system explained

The endocannabinoid system (ECS) is one of the most complex and extensive signaling networks in the human body. It consists of three components: endocannabinoids (cannabinoid-like molecules that the body produces itself), receptors (particularly CB1 and CB2), and enzymes that synthesize and break down the endocannabinoids.

CB1 receptors are primarily present in the brain and central nervous system and play a role in the regulation of pain, mood, memory, and motor control. CB2 receptors are mainly found in immune cells and peripheral tissues and are involved in the regulation of inflammation and immune response.

CBD does not bind directly to CB1 or CB2 like THC does. Instead, CBD modulates the activity of the ECS indirectly – among other things by inhibiting the enzyme that breaks down anandamide (an endocannabinoid associated with well-being and pain modulation), thereby increasing the concentration of anandamide in the body. CBD also interacts with serotonin, dopamine, and GABA receptors, which explains its broad spectrum of action.

History and scientific background

Although the use of hemp as a medicinal plant dates back thousands of years – it is documented in Egyptian, Chinese, and Greek medicine – CBD was not first isolated as a separate compound until 1940 by American chemist Roger Adams at the University of Illinois. The complete chemical structure of CBD was elucidated in 1963 by Israeli researcher Raphael Mechoulam, who also isolated THC and is considered the discoverer of the endocannabinoid system.

For decades, CBD remained in the scientific shadow of THC, but starting in the 1990s—with the discovery of the ECS and increasing interest in cannabinoids as therapeutic substances—research into CBD grew explosively. Today, CBD is the most extensively researched plant-based cannabinoid in the world, with thousands of published studies into its potential effects on anxiety, inflammation, sleep, neuropathic pain, epilepsy, and autoimmune disorders, among others. In 2018, the US FDA approved the first CBD-based medication—Epidiolex—for the treatment of certain severe forms of epilepsy in children.

Which strength should I choose? From 2,5% to 40%

One of the most frequently asked questions about CBD oil is: which percentage is right for me? The strength of a CBD oil refers to the concentration of CBD in the oil – expressed as a percentage of the total volume. A higher concentration means more CBD per drop, so you need fewer drops for the same dose. As a rule of thumb:

• 2,5% CBD oil – The mildest entry-level formula. Ideal for beginners discovering CBD for the first time or for those seeking very low daily support. Each drop contains approximately 1,25mg of CBD.
• 5% CBD oil – The most popular choice for beginners and for light daily use. Provides approximately 2,5mg CBD per drop. Suitable for those seeking relaxation, better sleep, or mild stress relief.
• 10% CBD oil – A balanced middle category for those who already have some experience or desire a clearer effect. Approximately 5mg CBD per drop. The best-selling strength for daily use by advanced users.
• 20% CBD oil – A powerful formula for those who consciously work with higher doses or have specific support needs. Approximately 10mg CBD per drop.
• 30% CBD oil – A concentrated formula for experienced users with an increased CBD requirement. Approximately 15mg CBD per drop.
• 40% CBD oil – The most powerful formula in the range. Approximately 20mg CBD per drop. Recommended exclusively for experienced users who work consciously and purposefully with high CBD doses.

As a general guideline for beginners, a starting dose of 5 to 10 mg of CBD per day is recommended, to be gradually increased until the desired effect is achieved. Always consult a doctor if you are taking medication or have a medical condition before starting CBD.

The complete CBD range from Cannabas

All CBD products in the Dr Smart Shop range come from cannabis – a quality brand that distinguishes itself through its transparent production, documented lab analyses (Certificate of Analysis), and wide range. The CBD oils are available in bottles of 10ml en 30ml, equipped with an accurate dropper for easy dosing.

• Cannabis CBD Oil 2,5% – from €11,95 – The gentle entry-level formula. Available in 10ml and 30ml. Ideal for those trying CBD oil for the first time or who need subtle daily support.
• Cannabis CBD Oil 5% – from €19,00 – The most popular choice in the range. Available in 10ml and 30ml. A good balance between mild action and affordable daily use.
• Cannabis CBD Oil 10% – from €39,00 – The most popular strength for advanced users. Available in 10ml and 30ml. Offers clearer and more consistent support than the lower strengths.
• Cannabis CBD Oil 20% – from €79,00 – A powerful formula for those who consciously use higher doses. Available in 10ml and 30ml. Recommended for those who have already tested the lower strengths and are looking for a greater effect.
• Cannabis CBD Oil 30% – from €119,00 – A concentrated premium formula for experienced users. Available in 10ml and 30ml. The 30ml bottle offers the best price per mg of CBD in the higher segment.
• Cannabis CBD Oil 40% - € 159,00 – The most powerful CBD oil in the range. Exclusively for experienced users who consciously work with high CBD concentrations. Certificate of Analysis available.

CBG, CBC and CBN: the other cannabinoids

In addition to CBD, the hemp plant contains more than a hundred other cannabinoids, a number of which have promising properties that are being scientifically investigated. Through Cannabas, Dr Smart Shop offers three additional cannabinoid oils: CBG, CBC, and CBN. Each has its own profile and specific area of ​​application.

CBG Oil – The "mother cannabidioid"

Cannabas CBG Oil – €29,00 contains cannabigerol (CBG) – a cannabinoid also known as the "mother cannabidioid," because CBG is the biosynthetic precursor to both CBD and THC. In the early growth phase of the hemp plant, CBG is the dominant cannabinoid; as the plant matures, it is converted into CBD, THC, and other cannabinoids.

CBG is non-psychoactive and is being investigated for its potential as an antibacterial agent, a neuroprotective substance, and as a digestive aid. CBG binds directly to both CB1 and CB2 receptors, which distinguishes it from CBD. Users describe CBG as clearer and more energetic in character than CBD, without the sedative effect that some people experience at higher CBD doses.

CBC Oil – Inflammation and pain modulation

Cannabas CBC Oil – €59,00 contains cannabichromene (CBC) – one of the least known but most fascinating cannabinoids. CBC is the third most abundant cannabinoid in the hemp plant after THC and CBD, but has long flown under the radar due to researchers' focus on the first two.

CBC acts via receptors different from CBD – specifically the TRPV1 and TRPA1 receptors involved in pain and temperature modulation. Scientific research suggests that CBC may play a role in inflammation modulation, neuroprotection, and the support of neurogenesis – the production of new brain cells. CBC works particularly synergistically with CBD and other cannabinoids via the so-called entourage effect.

CBN Oil – Sleep and relaxation

Cannabas CBN Oil – €49,00 contains cannabinol (CBN) – a cannabinoid formed by the oxidation and breakdown of THC. CBN is weakly psychoactive at very high doses but is considered non-psychoactive in standard supplement dosages.

CBN is popularly known as the "sleep cannabinoid," although scientific evidence for this is still limited. However, CBN does have a clear interaction with the CB1 receptor and is being investigated for its sedative, anti-inflammatory, and antibacterial properties. Users who take CBN report a calm, relaxing effect that can promote falling asleep. CBN is particularly popular as an evening formula, possibly combined with CBD oil.

CBD Cosmetics: Ointment and Massage Oil

In addition to internal CBD oils, Dr Smart Shop, through Cannabas, also offers two cosmetic products that apply CBD topically—that is, externally to the skin. Topical CBD products work locally via skin receptors and do not reach the bloodstream, making them particularly suitable for targeted local application.

Cannabas CBD Ointment – ​​Ointment – ​​€22,00

Cannabas CBD Ointment is a rich, restorative skin ointment based on CBD extract in a protective ointment base. The opioid and endocannabinoid receptors in the skin respond to topical CBD, allowing local application to provide targeted support for dry or irritated skin, muscle tension, or joint complaints. The CBD Ointment is suitable for use on all skin types and is free from artificial fragrances. It can be used as daily skin care or targeted at specific areas.

Cannabis CBD Massage Oil – €29,00

Cannabas CBD Massage Oil is a liquid, gentle oil formulated for use during massage. The combination of CBD extract with a portable vegetable oil base makes the product particularly suitable for deep relaxation massages, sports massages, or simply as a moment of pampering for body and mind. The oil absorbs well into the skin and leaves no greasy film behind. Particularly popular in combination with internal CBD oil for combined internal and external support.

Usage, dosage, and storage tips

CBD oil is preferably taken sublingually – that is, drops are placed under the tongue and held there for 30 to 60 seconds before swallowing. The mucous membranes under the tongue absorb CBD quickly and directly into the bloodstream, resulting in faster absorption than when the oil is swallowed directly. The effects typically begin within 15 to 45 minutes.

General dosage guidelines for beginners:

• Weeks 1 to 2: 5 to 10mg CBD per day (for 5% oil: 2 to 4 drops, for 10%: 1 to 2 drops)
• Weeks 3 to 4: Gradually build up to 10 to 20 mg per day if the desired effect has not yet been achieved.
• Maintenance: use the lowest effective dose – more is not always better with CBD

Practical tips for use and storage:

• Preferably take CBD oil at a fixed time each day – consistency is more important than timing.
• Take CBD oil with a meal containing fats for better absorption of fat-soluble CBD.
• Store CBD oil in a cool, dark place – preferably in the refrigerator – to preserve quality and potency. Opened bottles will keep for 12 to 18 months if stored correctly.
• Shake the bottle well before use to distribute the CBD evenly in the carrier oil.
• Do not combine CBD oil with grapefruit juice – grapefruit inhibits the enzyme CYP3A4, which is involved in the metabolism of CBD, potentially leading to increased blood concentration.
• Consult a doctor if you are taking blood thinners or other medications before taking CBD oil – CBD can affect the action of certain medications.

CBD Oil in the Dr Smart Shop CBD shop

The CBD Oil collection is part of the broader CBDshop category at Dr Smart Shop, which, in addition to CBD oil, also offers separate collections for CBG Oil , CBC Oil , CBN Oil , CBD Cosmetics , and CBD Hash . Together, these categories offer a complete and wide range of cannabinoids for every use and preference.

All CBD products are shipped quickly from our own stock. Orders placed on business days before 16:00 PM are shipped the same day in discreet packaging. Free shipping on orders over €45. Use discount code TRUFFEL10 for 10% off the entire range.

Frequently Asked Questions about CBD Oil

CBD oil is one of the most versatile and best-researched natural supplements currently available. With Cannabas ’ extensive and transparent range – from the mild 2,5% formula for beginners to the powerful 40% oil for advanced users, supplemented with CBG , CBC , CBN , and cosmetics – Dr Smart Shop offers the right choice for every user and every goal. View the full range on the CBD Oil page and discover which product best suits your situation.